SCHEMBL20004573

SCHEMBL20004573

CCCCOc1cc(F)c(C#Cc2ccc(CCc3ccc(-c4ccc(C)cc4)cc3)cc2)c(OC)c1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 2/20 0.39
ACACB O00763 7/20 0.39
RARA P10276 1/20 0.38
RARB P10826 1/20 0.38
LMNA P02545 2/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
PKM P14618 1/20 0.37
ERN1 O75460 1/20 0.35
MAOB P27338 2/20 0.35
KMT2A Q03164 1/20 0.35
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
KCNH2 Q12809 1/20 0.34
FFAR1 O14842 1/20 0.34
FFAR4 Q5NUL3 1/20 0.34
MAOA P21397 1/20 0.34
S1PR1 P21453 1/20 0.34
S1PR3 Q99500 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20005203 0.86 ACACB (0.45) MCHR1ACACBLMNAMAOBMAOA
SCHEMBL20004857 0.82 RARA (0.40) MCHR1RARARARBMAPTERN1
SCHEMBL20004775 0.82 ERN1 (0.40) MCHR1ACACBRARARARBERN1
SCHEMBL19999498 0.80 ACACB (0.44) MCHR1ACACBLMNAPKMERN1
SCHEMBL20004687 0.80 RARA (0.37) MCHR1ACACBRARARARBERN1
SCHEMBL19999435 0.79 FFAR1 (0.35) MCHR1ACACBMAOBKMT2AFFAR1
SCHEMBL20004548 0.79 DRD2 (0.40) ACACBLMNAALDH1A1MAPTKMT2A
SCHEMBL19999373 0.79 TUBB4A (0.45) MCHR1ACACBERN1MAOBMAOA
SCHEMBL20005217 0.79 ERN1 (0.37) MCHR1ACACBRARARARBERN1
SCHEMBL19999557 0.78 ACACB (0.42) MCHR1ACACBRARARARBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3299439-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC Corporation (JP) 2018-03-28 EP disclosed