SCHEMBL20005203

SCHEMBL20005203

CCCCOc1cc(F)c(C#Cc2ccc(OCCC)cc2)c(OC)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACACB O00763 13/20 0.45
TUBB4A P04350 1/20 0.42
TUBB P07437 1/20 0.42
TUBA3C P0DPH7 1/20 0.42
TUBA1B P68363 1/20 0.42
TUBA4A P68366 1/20 0.42
TUBB4B P68371 1/20 0.42
TUBB3 Q13509 1/20 0.42
TUBB2A Q13885 1/20 0.42
TUBB8 Q3ZCM7 1/20 0.42
TUBA3E Q6PEY2 1/20 0.42
TUBA1A Q71U36 1/20 0.42
TUBA1C Q9BQE3 1/20 0.42
TUBB6 Q9BUF5 1/20 0.42
TUBB2B Q9BVA1 1/20 0.42
TUBB1 Q9H4B7 1/20 0.42
MAOB P27338 2/20 0.40
MCHR1 Q99705 1/20 0.39
AHR P35869 1/20 0.39
MAOA P21397 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19999373 0.87 TUBB4A (0.45) ACACBTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL20004573 0.86 MCHR1 (0.39) ACACBMAOBMCHR1MAOALMNA
SCHEMBL14887180 0.81 LTA4H (0.40) ACACBHTT
SCHEMBL20004548 0.79 DRD2 (0.40) ACACBLMNASMN1; SMN2
SCHEMBL19999372 0.79 ACACB (0.37) ACACBTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL20005283 0.79 ERN1 (0.38) ACACBTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL20005290 0.78 ERN1 (0.41) ACACBTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL14964488 0.77 RARB (0.42) ACACBTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL20004775 0.77 ERN1 (0.40) ACACBTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL20004857 0.77 RARA (0.40) MAOBMCHR1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3299439-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC Corporation (JP) 2018-03-28 EP disclosed