Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2006267 | 0.95 | FAAH (0.35) | FAAHSCDSCD5ALDH1A1LMNA | |
| SCHEMBL2004961 | 0.92 | FAAH (0.33) | FAAHSCDSCD5ALDH1A1LMNA | |
| SCHEMBL2003449 | 0.91 | LMNA (0.38) | FAAHSCDSCD5ALDH1A1LMNA | |
| SCHEMBL2012375 | 0.91 | FAAH (0.37) | FAAHSCDSCD5ALDH1A1LMNA | |
| SCHEMBL2008038 | 0.90 | FAAH (0.39) | L3MBTL1FAAHALDH1A1LMNAMAPT | |
| SCHEMBL2005377 | 0.90 | L3MBTL1 (0.36) | L3MBTL1FAAHALDH1A1LMNAMAPT | |
| SCHEMBL2009971 | 0.90 | L3MBTL1 (0.37) | L3MBTL1FAAHALDH1A1LMNAMAPT | |
| SCHEMBL2010346 | 0.90 | PLA2G2A (0.37) | FAAHSCDSCD5ALDH1A1LMNA | |
| SCHEMBL2002426 | 0.89 | SLC26A4 (0.34) | FAAHSCDSCD5LMNAMAPT | |
| SCHEMBL2002081 | 0.88 | L3MBTL1 (0.35) | L3MBTL1ALDH1A1LMNAMAPTALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960544-B2 | Useful indole compounds | IRONWOOD PHARMACEUTICALS, INC. (US) | 2011-06-14 | — | — | US | disclosed |