SCHEMBL20008182

SCHEMBL20008182

COc1ccc(C(I)(c2ccc(OC)cc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.58
CA2 P00918 2/20 0.58
CA7 P43166 2/20 0.58
CA9 Q16790 2/20 0.58
CA12 O43570 1/20 0.58
CA14 Q9ULX7 1/20 0.58
ACHE P22303 1/20 0.48
TDP1 Q9NUW8 5/20 0.46
MAPK1 P28482 4/20 0.46
ALDH1A1 P00352 5/20 0.44
MAPT P10636 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
RECQL P46063 2/20 0.44
KDM4E B2RXH2 1/20 0.44
NPC1 O15118 1/20 0.44
GAA P10253 1/20 0.44
THRB P10828 1/20 0.44
RAB9A P51151 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
CYP3A4 P08684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23157234 0.91 CA4 (0.54) CA1CA2CA7CA9CA12
SCHEMBL18196315 0.91 CA4 (0.54) CA1CA2CA7CA9CA12
SCHEMBL10234328 0.82 CA1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL18535888 0.80 CA1 (0.52) CA1CA2CA7CA9CA12
SCHEMBL17151421 0.80 CA1 (0.52) CA1CA2CA7CA9CA12
SCHEMBL3976751 0.78 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL2636287 0.78 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL3241488 0.78 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL12227837 0.78 CA1 (0.65) CA1CA2CA7CA9CA12
SCHEMBL30676990 0.78 CA1 (0.65) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3954823-B1 MEMBRANE FOR A DEWATERING PRESS MAXI PRESS ELASTOMERTECHNIK GMBH (DE) 2024-05-08 EP claimed
US-11786600-B2 Cliptac composition OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2023-10-17 US claimed
CN-114280552-A Sidelobe cancellation method for radar strong clutter region 武汉滨湖电子有限责任公司 2022-04-05 CN claimed
EP-3954823-A1 MEMBRANE FOR A DEWATERING PRESS MAXI-PRESS Elastomertechnik GmbH (DE) 2022-02-16 EP claimed
US-20260071198-A1 CRISPR ENZYMES AND SYSTEMS WITH MODIFIED PAM SPECIFICITY THE BROAD INSTITUTE, INC. (US) 2026-03-12 US disclosed
US-12517131-B2 Methods for labeling eukaryotic cells from a multicellular organism as well as for treating and/or diagnosing a cancer using modified monosaccharide compounds DIAMIDEX (FR) 2026-01-06 US disclosed
US-20260000700-A1 TARGETED LINEAR CONJUGATES COMPRISING POLYETHYLENEIMINE AND POLYETHYLENE GLYCOL AND POLYPLEXES COMPRISING THE SAME TARGIMMUNE THERAPEUTICS AG (CH) 2026-01-01 US disclosed
US-20260000771-A1 PSMA-TARGETING LINEAR CONJUGATES COMPRISING POLYETHYLENEIMINE AND POLYETHYLENE GLYCOL AND POLYPLEXES COMPRISING THE SAME TARGIMMUNE THERAPEUTICS AG (CH) 2026-01-01 US disclosed
WO-2025238236-A1 POLYPLEXES OF NUCLEIC ACIDS AND TARGETED CONJUGATES COMPRISING POLYETHYLENEIMINE AND POLYETHYLENE GLYCOL TARGIMMUNE THERAPEUTICS AG (CH) 2025-11-20 WO disclosed
EP-4649160-A1 CHEMICALLY-MODIFIED ADENO-ASSOCIATED VIRUS Nantes Université (FR) 2025-11-19 EP disclosed
EP-4649137-A1 METHODS FOR CELL SURFACE REMODELING Nantes Université (FR) 2025-11-19 EP disclosed
US-20250332286-A1 CHEMICALLY-MODIFIED ADENO-ASSOCIATED VIRUSES CENTRE NAT RECH SCIENT (FR) 2025-10-30 US disclosed
EP-4017859-A1 ALKYL QUARTERNARY AMMONIUM TRYPTAMINES AND THEIR THERAPEUTIC USES Caamtech, LLC (US) 2022-06-29 EP disclosed
US-20220146516-A1 METHODS FOR LABELING EUKARYOTIC CELLS FROM A MULTICELLULAR ORGANISM AS WELL AS FOR TREATING AND/OR DIAGNOSING A CANCER USING MODIFIED MONOSACCHARIDE COMPOUNDS DIAMIDEX (FR) 2022-05-12 US disclosed
EP-3990434-A1 COMPOUNDS HAVING ANTIMALARIAL ACTIVITY Nanyang Technological University (SG) 2022-05-04 EP disclosed
US-20220112162-A1 ALKYL QUATERNARY AMMONIUM TRYPTAMINES AND THEIR THERAPEUTIC USES CAAMTECH, INC. (US) 2022-04-14 US disclosed
CN-114280552-A Sidelobe cancellation method for radar strong clutter region 武汉滨湖电子有限责任公司 2022-04-05 CN disclosed
CN-114189815-A Method and apparatus for terminal communication in mobile communication system 三星电子株式会社 2022-03-15 CN disclosed
WO-2022047580-A1 HYDROXYLATED PSILOCYBIN DERIVATIVES AND METHODS OF USING MAGICMED INDUSTRIES INC. (CA) 2022-03-10 WO disclosed
WO-2018057430-A1 SYNTHESIS OF BACKBONE MODIFIED MORPHOLINO OLIGONUCLEOTIDES AND CHIMERAS USING PHOSPHORAMIDITE CHEMISTRY THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2018-03-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071198-A1 CRISPR ENZYMES AND SYSTEMS WITH MODIFIED PAM SPECIFICITY CPSF1, CPSF6, CPN1 CA1 3113/4885CA2 2663/4885CA7 2301/4885
US-20260000771-A1 PSMA-TARGETING LINEAR CONJUGATES COMPRISING POLYETHYLENEIMINE AND POLYETHYLENE GLYCOL AND POLYPLEXES COMPRISING THE SAME PSMA1, PSMA3, PSMA2 CA1 150/4885CA2 507/4885CA7 767/4885
US-20260000700-A1 TARGETED LINEAR CONJUGATES COMPRISING POLYETHYLENEIMINE AND POLYETHYLENE GLYCOL AND POLYPLEXES COMPRISING THE SAME CTDSP1, POLM, MCTS1 CA1 2387/4885CA2 2927/4885CA7 4147/4885
US-11786600-B2 Cliptac composition UBE3C, CBLC, STUB1 CA1 3846/4885CA2 4609/4885CA7 4539/4885
US-20250332286-A1 CHEMICALLY-MODIFIED ADENO-ASSOCIATED VIRUSES AMDHD2, AADAC, ALDH1A2 CA1 2289/4885CA2 1907/4885CA7 720/4885
US-20220112162-A1 ALKYL QUATERNARY AMMONIUM TRYPTAMINES AND THEIR THERAPEUTIC USES SLC18A1, HNMT, TPH1 CA1 2883/4885CA2 1048/4885CA7 1608/4885
US-20220146516-A1 METHODS FOR LABELING EUKARYOTIC CELLS FROM A MULTICELLULAR ORGANISM AS WELL AS FOR TREATING AND/OR DIAGNOSING A CANCER USING MODIFIED MONOSACCHARIDE COMPOUNDS ALG1, ALG8, FUCA1 CA1 2165/4885CA2 2876/4885CA7 652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.