Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008233 | 0.68 | RAB9A (0.39) | NPC1RAB9AKMT2A | |
| SCHEMBL20133776 | 0.57 | ESR1 (0.34) | — | |
| SCHEMBL11209782 | 0.55 | ALDH1A1 (0.44) | KMT2A | |
| SCHEMBL20133768 | 0.55 | PRKCI (0.32) | — | |
| Hydrochloric Acid SCHEMBL11212030 | 0.55 | ALDH1A1 (0.43) | — | |
| SCHEMBL24100538 | 0.53 | HPGD (0.53) | NPC1RAB9AKMT2A | |
| SCHEMBL19198529 | 0.52 | CYP3A4 (0.36) | — | |
| SCHEMBL3308433 | 0.52 | L3MBTL1 (0.45) | NPC1RAB9AKMT2A | |
| SCHEMBL31606399 | 0.52 | MEN1 (0.44) | KMT2A | |
| SCHEMBL20160730 | 0.52 | ESR1 (0.35) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |