SCHEMBL20008656

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20008654	0.89	FTO (0.45)	FTOPRSS1F2KLKB1KLK1
	SCHEMBL20008657	0.83	FTO (0.43)	FTOPRSS1F2KLKB1KLK1
	SCHEMBL20008653	0.82	PLAU (0.51)	FTOPRSS1F2KLKB1KLK1
	SCHEMBL20008652	0.81	F12 (0.46)	FTOPRSS1F2KLKB1KLK1
	SCHEMBL20008659	0.81	FTO (0.49)	FTOPRSS1F2KLKB1KLK1
	Nafamostat SCHEMBL29429443	0.81	PRSS1 (0.64)	FTOPRSS1F2KLKB1KLK1
	Nafamostat SCHEMBL29429445	0.81	PRSS1 (0.64)	FTOPRSS1F2KLKB1KLK1
	Nafamostat SCHEMBL16069975	0.81	PRSS1 (0.64)	FTOPRSS1F2KLKB1KLK1
	Nafamostat SCHEMBL135503	0.81	PRSS1 (0.64)	FTOPRSS1F2KLKB1KLK1
	Nafamostat SCHEMBL1568755	0.80	FTO (0.70)	FTOPRSS1F2KLKB1KLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.