Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.46 |
| ▸ | TMPRSS15 | P98073 | 13/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 12/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008719 | 0.95 | ITGB3 (0.48) | ITGB3ITGA2BTMPRSS15PRSS1 | |
| SCHEMBL20008713 | 0.94 | FTO (0.42) | ITGB3ITGA2BTMPRSS15PRSS1FOLH1 | |
| SCHEMBL20008721 | 0.93 | ITGB3 (0.48) | ITGB3ITGA2BTMPRSS15PRSS1 | |
| SCHEMBL20008712 | 0.89 | ITGB3 (0.44) | ITGB3ITGA2BTMPRSS15PRSS1FOLH1 | |
| SCHEMBL20008720 | 0.87 | ITGB3 (0.44) | ITGB3ITGA2BTMPRSS15PRSS1FOLH1 | |
| SCHEMBL20008717 | 0.83 | ITGB3 (0.51) | ITGB3ITGA2BTMPRSS15PRSS1FOLH1 | |
| SCHEMBL20008696 | 0.77 | ITGB3 (0.52) | ITGB3ITGA2B | |
| SCHEMBL20008642 | 0.77 | ITGB3 (0.49) | ITGB3ITGA2BPRSS1 | |
| SCHEMBL20008716 | 0.73 | TMPRSS15 (0.44) | ITGB3ITGA2BTMPRSS15PRSS1FOLH1 | |
| SCHEMBL20008741 | 0.71 | ITGB3 (0.50) | ITGB3ITGA2BTMPRSS15PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180085366-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180085366-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | OPRM1, OPRK1, OPRD1 | ITGB3 2592/4885ITGA2B 2485/4885TMPRSS15 87/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.