Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.44 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | S100B | P04271 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008744 | 0.92 | FTO (0.46) | ITGB3ITGA2BMEN1HPGDKMT2A | |
| SCHEMBL20008762 | 0.91 | KMT2A (0.43) | ITGB3ITGA2BMEN1HPGDKMT2A | |
| SCHEMBL20008741 | 0.89 | ITGB3 (0.50) | ITGB3ITGA2BPRSS1PRMT1F2 | |
| SCHEMBL21920306 | 0.87 | ITGB3 (0.45) | ITGB3ITGA2BMEN1HPGDKMT2A | |
| SCHEMBL20008743 | 0.86 | TMPRSS2 (0.57) | PRSS1PRMT1F2ST14F10 | |
| SCHEMBL20008628 | 0.86 | ITGB3 (0.53) | ITGB3ITGA2BPRSS1PRMT1F2 | |
| SCHEMBL20008755 | 0.81 | TMPRSS2 (0.66) | PRSS1PRMT1F2ST14F10 | |
| SCHEMBL20008757 | 0.80 | F12 (0.51) | ITGB3ITGA2BPRSS1PRMT1F2 | |
| SCHEMBL20008632 | 0.78 | FTO (0.49) | ITGB3ITGA2BPRSS1PRMT1F2 | |
| SCHEMBL20008711 | 0.78 | PRSS1 (0.67) | PRSS1PRMT1F2ST14F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180085366-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180085366-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | OPRM1, OPRK1, OPRD1 | ITGB3 2592/4885ITGA2B 2485/4885MEN1 4875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.