Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F12 | P00748 | 6/20 | 0.51 |
| ▸ | F10 | P00742 | 5/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.51 |
| ▸ | F2 | P00734 | 4/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.51 |
| ▸ | C1R | P00736 | 2/20 | 0.51 |
| ▸ | KLK1 | P06870 | 2/20 | 0.51 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.51 |
| ▸ | PLG | P00747 | 2/20 | 0.51 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.51 |
| ▸ | MLNR | O43193 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPN | P05981 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | C1S | P09871 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008741 | 0.91 | ITGB3 (0.50) | F10PRSS1F2ITGB3ITGA2B | |
| SCHEMBL20008744 | 0.90 | FTO (0.46) | F12F10PRSS1F2ITGB3 | |
| SCHEMBL20008763 | 0.84 | PRSS1 (0.60) | F12F10PRSS1F2ITGB3 | |
| SCHEMBL20008714 | 0.83 | PRSS1 (0.63) | F12F10PRSS1F2ITGB3 | |
| SCHEMBL21119487 | 0.82 | FTO (0.42) | F12F10PRSS1F2ITGB3 | |
| SCHEMBL20012192 | 0.80 | FTO (0.41) | F12F10PRSS1F2ITGB3 | |
| SCHEMBL20008745 | 0.80 | ITGB3 (0.47) | F10PRSS1F2ITGB3ITGA2B | |
| SCHEMBL20008712 | 0.80 | ITGB3 (0.44) | F12F10PRSS1F2ITGB3 | |
| SCHEMBL20008632 | 0.80 | FTO (0.49) | F12F10PRSS1F2ITGB3 | |
| SCHEMBL18720302 | 0.79 | PRSS1 (0.60) | F12F10PRSS1F2ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180085366-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180085366-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | OPRM1, OPRK1, OPRD1 | F12 3544/4885F10 3799/4885PRSS1 952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.