Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.46 |
| ▸ | ACR | P10323 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008762 | 0.88 | KMT2A (0.43) | KMT2APRSS1ACRMAPTCYP3A4 | |
| SCHEMBL20008743 | 0.87 | TMPRSS2 (0.57) | PRSS1ACRTMPRSS2CYP2D6 | |
| SCHEMBL20008749 | 0.82 | KMT2A (0.53) | KMT2APRSS1ACRMAPTMEN1 | |
| SCHEMBL20008755 | 0.81 | TMPRSS2 (0.66) | PRSS1ACRTMPRSS2CYP2D6 | |
| SCHEMBL9617543 | 0.81 | HRH3 (0.54) | KMT2APRSS1ACRMAPTMEN1 | |
| SCHEMBL7328271 | 0.80 | ACR (0.58) | KMT2APRSS1ACRMAPTMEN1 | |
| SCHEMBL10956570 | 0.80 | KMT2A (0.56) | KMT2APRSS1ACRMAPTCYP3A4 | |
| SCHEMBL9785653 | 0.80 | ALDH1A1 (0.44) | KMT2APRSS1ACRMAPTMEN1 | |
| SCHEMBL20008750 | 0.80 | F12 (0.55) | PRSS1ACRMAPTADRA2BTMPRSS2 | |
| SCHEMBL9785626 | 0.80 | KMT2A (0.45) | KMT2APRSS1ACRMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180085366-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180085366-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | OPRM1, OPRK1, OPRD1 | KMT2A 1946/4885PRSS1 952/4885ACR 4881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.