SCHEMBL20008914

SCHEMBL20008914

CCC(C)(OC(=O)c1cccc2c(C(=O)OC(C)(CS(=O)(=O)O)C(F)(F)F)cccc12)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK1 Q15118 1/20 0.32
PDK2 Q15119 1/20 0.32
PDK3 Q15120 1/20 0.32
PDK4 Q16654 1/20 0.32
TSHR P16473 1/20 0.32
ADRB2 P07550 1/20 0.31
ADRB1 P08588 1/20 0.31
ADRB3 P13945 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
CDC25B P30305 1/20 0.31
AKR1B10 O60218 1/20 0.31
AKR1A1 P14550 1/20 0.31
AKR1B1 P15121 1/20 0.31
ELANE P08246 1/20 0.31
PRTN3 P24158 1/20 0.31
KDM4E B2RXH2 2/20 0.31
BRD4 O60885 1/20 0.30
CDK4 P11802 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20008933 0.95 CYP1A2 (0.33) TSHRCYP1A2CYP2D6CYP2C19ELANE
SCHEMBL16020244 0.88 ADRB2 (0.43) TSHRADRB2ADRB1ADRB3CYP1A2
SCHEMBL20008928 0.83 CYP2C19 (0.40) PDK1PDK2PDK3PDK4CYP1A2
SCHEMBL19846366 0.81
SCHEMBL16020253 0.81 LMNA (0.44) TSHRADRB2ADRB1ADRB3ELANE
SCHEMBL16020249 0.81 ALDH1A1 (0.40) TSHRELANEPRTN3ALOX15ALDH1A1
SCHEMBL16020243 0.76 CYP2D6 (0.47) TSHRADRB2ADRB1ADRB3CYP1A2
SCHEMBL16020248 0.75 ALDH1A1 (0.44) CYP1A2CYP2C19KDM4EALOX15ALDH1A1
SCHEMBL16020238 0.74 KDM4E (0.40) CYP2D6ELANEPRTN3KDM4EALDH1A1
SCHEMBL13079578 0.72 KDM4E (0.42) ADRB2ADRB1ADRB3CDC25BKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180085019-A1 ADHESIVE COMPOSITION, BIO-ELECTRODE, AND METHOD FOR MANUFACTURING A BIO-ELECTRODE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-03-29 US disclosed