SCHEMBL20008933

SCHEMBL20008933

CCC(C)(OC(=O)c1ccc(C(=O)OC(C)(CS(=O)(=O)O)C(F)(F)F)c2ccccc12)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
BRD4 O60885 1/20 0.33
TSHR P16473 1/20 0.32
NR4A2 P43354 1/20 0.31
ELANE P08246 1/20 0.31
PRTN3 P24158 1/20 0.31
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
PLK1 P53350 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20008914 0.95 PDK1 (0.32) CYP1A2CYP2D6CYP2C19BRD4TSHR
SCHEMBL16020244 0.85 ADRB2 (0.43) CYP1A2CYP2D6TSHRNR4A2ALDH1A1
SCHEMBL20008928 0.83 CYP2C19 (0.40) CYP1A2CYP2D6CYP2C19ELANEMAPT
SCHEMBL16020253 0.81 LMNA (0.44) TSHRELANEPRTN3ALDH1A1MAPT
SCHEMBL16020249 0.81 ALDH1A1 (0.40) TSHRELANEPRTN3ALDH1A1
SCHEMBL16020243 0.79 CYP2D6 (0.47) CYP1A2CYP2D6CYP2C19TSHRALDH1A1
SCHEMBL16020248 0.78 ALDH1A1 (0.44) CYP1A2CYP2C19ALDH1A1MAPT
SCHEMBL19846366 0.77
SCHEMBL16020238 0.77 KDM4E (0.40) CYP2D6ELANEPRTN3ALDH1A1MAPT
SCHEMBL16020246 0.72 GABBR2 (0.41) ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180085019-A1 ADHESIVE COMPOSITION, BIO-ELECTRODE, AND METHOD FOR MANUFACTURING A BIO-ELECTRODE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-03-29 US disclosed