SCHEMBL20008928

SCHEMBL20008928

CCC(C)(OC(=O)c1ccc(C(=O)OC(C)(CS(=O)(=O)O)C(F)(F)F)cc1)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
PDK1 Q15118 1/20 0.39
PDK2 Q15119 1/20 0.39
PDK3 Q15120 1/20 0.39
PDK4 Q16654 1/20 0.39
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
CA12 O43570 2/20 0.38
CA9 Q16790 2/20 0.38
CA14 Q9ULX7 2/20 0.38
HPGD P15428 3/20 0.34
STS P08842 2/20 0.33
RECQL P46063 1/20 0.33
ELANE P08246 1/20 0.33
LMNA P02545 2/20 0.32
POLB P06746 1/20 0.32
MAPK1 P28482 2/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16020243 0.87 CYP2D6 (0.47) CYP2C19CYP1A2CYP2D6CA1CA2
SCHEMBL18561117 0.87 ALDH1A1 (0.39) CYP2C19CYP1A2CYP2D6PDK1PDK2
SCHEMBL18561115 0.85 ELANE (0.46) CYP2C19CYP1A2CYP2D6STSELANE
SCHEMBL20008914 0.83 PDK1 (0.32) CYP2C19CYP1A2CYP2D6PDK1PDK2
SCHEMBL20008933 0.83 CYP1A2 (0.33) CYP2C19CYP1A2CYP2D6ELANEMAPT
SCHEMBL16020246 0.80 GABBR2 (0.41) HPGDPOLBMAPTGAA
SCHEMBL18561116 0.80 ELANE (0.44) CA1CA2CA12CA9CA14
SCHEMBL19846363 0.79 CA12 (0.32) CA1CA2CA12CA9CA14
SCHEMBL16020250 0.78 PTPRC (0.45) CYP2C19CYP1A2CYP2D6HPGDLMNA
SCHEMBL14473935 0.76 ADRB2 (0.47) CA1CA2LMNAPOLBMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180085019-A1 ADHESIVE COMPOSITION, BIO-ELECTRODE, AND METHOD FOR MANUFACTURING A BIO-ELECTRODE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-03-29 US disclosed