Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 19/20 | 0.41 |
| ▸ | BRAF | P15056 | 19/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22561899 | 0.69 | ADCY1 (0.37) | RAF1BRAFMAPT | |
| SCHEMBL23677290 | 0.64 | MEN1 (0.46) | MAPT | |
| SCHEMBL20009394 | 0.62 | BRAF (0.70) | RAF1BRAF | |
| SCHEMBL25739849 | 0.62 | SMN1; SMN2 (0.62) | MAPT | |
| SCHEMBL20009452 | 0.62 | RAF1 (0.44) | RAF1BRAF | |
| SCHEMBL20009643 | 0.61 | BRAF (0.43) | RAF1BRAFMAPT | |
| SCHEMBL20009709 | 0.60 | BRAF (0.39) | RAF1BRAF | |
| SCHEMBL20008439 | 0.59 | RAF1 (0.67) | RAF1BRAF | |
| SCHEMBL20008296 | 0.59 | SMARCA2 (0.40) | RAF1BRAF | |
| SCHEMBL20009443 | 0.58 | RAF1 (0.37) | RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |