Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 5/20 | 0.60 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.60 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.58 |
| ▸ | TTK | P33981 | 6/20 | 0.55 |
| ▸ | ULK1 | O75385 | 2/20 | 0.54 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.54 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.54 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.52 |
| ▸ | IGF1R | P08069 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20012920 | 0.93 | TTK (0.57) | INSRALKLRRK2TTKDCLK1 | |
| SCHEMBL20012945 | 0.85 | INSR (0.62) | INSRALKLRRK2DCLK1MAPK7 | |
| SCHEMBL20012903 | 0.84 | SYK (0.53) | TTKIGF1R | |
| SCHEMBL20012906 | 0.78 | CDK4 (0.46) | IGF1R | |
| SCHEMBL3720414 | 0.75 | INSR (0.67) | INSRALKLRRK2TTKULK1 | |
| SCHEMBL20012904 | 0.75 | CDK4 (0.54) | INSRALKTTKTNK2EGFR | |
| SCHEMBL29575617 | 0.75 | TTK (0.72) | INSRALKLRRK2TTKULK1 | |
| SCHEMBL12311873 | 0.74 | LRRK2 (1.00) | INSRALKLRRK2DCLK1TNK2 | |
| SCHEMBL20012936 | 0.73 | WEE1 (0.47) | EGFR | |
| SCHEMBL20012944 | 0.73 | TNK2 (0.53) | TNK2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018056621-A1 | NOVEL IMIDAZOLYL PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF CANCER | 재단법인 대구경북첨단의료산업진흥재단 | 2018-03-29 | — | — | WO | disclosed |