Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8849605 | 0.81 | DDB1 (0.53) | ADRA1APDPK1SIGMAR1DDB1CRBN | |
| SCHEMBL942815 | 0.76 | PDPK1 (0.43) | ADRA1APDPK1SIGMAR1TAS1R3TAS1R1 | |
| Ammonia Solution, Strong SCHEMBL8005893 | 0.74 | PDPK1 (0.42) | ADRA1APDPK1SIGMAR1TAS1R3TAS1R1 | |
| SCHEMBL10359793 | 0.71 | GID4 (0.51) | ADRA1ATAS1R3TAS1R1TAS1R2DDB1 | |
| SCHEMBL24118653 | 0.71 | SIGMAR1 (0.38) | SIGMAR1DDB1CRBNSLC6A2SLC6A4 | |
| SCHEMBL11216392 | 0.71 | SIGMAR1 (0.39) | ADRA1APDPK1SIGMAR1TAS1R3TAS1R1 | |
| SCHEMBL10492671 | 0.69 | IDO1 (0.40) | ADRA1APDPK1SIGMAR1GID4IDO1 | |
| SCHEMBL10492532 | 0.69 | HTR6 (0.41) | ADRA1APDPK1SIGMAR1GID4IDO1 | |
| SCHEMBL2083374 | 0.68 | PLA2G6 (0.49) | ADRA1APDPK1SIGMAR1ADRA2AADRA2B | |
| SCHEMBL11767850 | 0.68 | PRCP (0.56) | ADRA1APDPK1SIGMAR1GID4IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074375-B1 | NEW INDANYLOXYPHENYLCYCLOPROPANECARBOXYLIC ACIDS | BOEHRINGER INGELHEIM INT (DE) | 2018-04-04 | — | — | EP | disclosed |