Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8005893

Cc1ccc(C2CCc3ccccc32)c(C)c1C.N.N

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.42
ADRA1A P35348 2/20 0.42
SIGMAR1 Q99720 2/20 0.41
IDO1 P14902 2/20 0.39
GID4 Q8IVV7 1/20 0.38
TAS1R3 Q7RTX0 1/20 0.37
TAS1R1 Q7RTX1 1/20 0.37
TAS1R2 Q8TE23 1/20 0.37
CYP11B2 P19099 1/20 0.37
HTR2C P28335 1/20 0.37
MAOA P21397 2/20 0.36
MAOB P27338 2/20 0.36
DDB1 Q16531 1/20 0.36
CRBN Q96SW2 1/20 0.36
BCHE P06276 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
ACHE P22303 1/20 0.36
HTR6 P50406 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL942815 0.98 PDPK1 (0.43) PDPK1ADRA1ASIGMAR1IDO1GID4
SCHEMBL8849605 0.80 DDB1 (0.53) PDPK1ADRA1ASIGMAR1IDO1CYP11B2
SCHEMBL1046129 0.74 PDPK1 (0.40) PDPK1ADRA1ASIGMAR1IDO1GID4
SCHEMBL10492671 0.74 IDO1 (0.40) PDPK1ADRA1ASIGMAR1IDO1GID4
SCHEMBL20017784 0.74 ADRA1A (0.40) PDPK1ADRA1ASIGMAR1IDO1GID4
SCHEMBL28398229 0.73 GID4 (0.48) PDPK1ADRA1ASIGMAR1IDO1GID4
SCHEMBL10492532 0.71 HTR6 (0.41) PDPK1ADRA1ASIGMAR1IDO1GID4
Ammonia Solution, Strong SCHEMBL8210515 0.71 SIGMAR1 (0.60) ADRA1ASIGMAR1GID4CYP11B2HTR2C
SCHEMBL2083374 0.70 PLA2G6 (0.49) PDPK1ADRA1ASIGMAR1IDO1CYP11B2
SCHEMBL10359793 0.70 GID4 (0.51) ADRA1AIDO1GID4TAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975687-A4 PROCESS FOR MAKING POLYIMIDE-POLYAMIC ESTER COPOLYMERS OLIN MICROELECTRONIC CHEM INC (US) 2000-07-05 EP disclosed
EP-0975687-A1 PROCESS FOR MAKING POLYIMIDE-POLYAMIC ESTER COPOLYMERS Olin Microelectronic Chemicals, Inc. (US) 2000-02-02 EP disclosed
WO-1998046664-A1 PROCESS FOR MAKING POLYIMIDE-POLYAMIC ESTER COPOLYMERS OLIN MICROELECTRONIC CHEMICALS, INC. (US) 1998-10-22 WO disclosed