Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20021165 | 0.87 | KDM4E (0.52) | PLA2G2AKDM4EESR1ESR2CYP19A1 | |
| SCHEMBL27928087 | 0.80 | POLB (0.45) | KDM4EESR1ESR2FABP3FABP4 | |
| SCHEMBL3323941 | 0.76 | KDM4E (0.51) | KDM4EDHODHFABP3FABP4FABP5 | |
| SCHEMBL245474 | 0.76 | PLA2G2A (0.38) | PLA2G2AESR1ESR2CYP19A1DHODH | |
| SCHEMBL15182627 | 0.75 | PLA2G2A (0.41) | PLA2G2AESR1ESR2CYP19A1DHODH | |
| SCHEMBL244126 | 0.75 | PSIP1 (0.45) | PLA2G2AESR1ESR2CYP19A1DHODH | |
| SCHEMBL27921801 | 0.73 | GPR84 (0.41) | KDM4EFABP3FABP4FABP5KCNH2 | |
| SCHEMBL3342040 | 0.71 | NOS1 (0.34) | KDM4EDHODH | |
| SCHEMBL20021110 | 0.71 | KDM4E (0.45) | KDM4EDHODHALDH1A1 | |
| SCHEMBL20021083 | 0.70 | KMT2A (0.51) | KDM4EKCNH2CYP3A4ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588455-B1 | 2-QUINOLINYL-ACETIC ACID DERIVATIVES AS HIV ANTIVIRAL COMPOUNDS | GILEAD SCIENCES INC (US) | 2018-04-04 | — | — | EP | disclosed |