Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20030008 | 0.97 | KDM4E (0.42) | KDM4EATML3MBTL1NPY5RSMN1; SMN2 | |
| SCHEMBL20029869 | 0.97 | KDM4E (0.42) | KDM4EATML3MBTL1NPY5RSMN1; SMN2 | |
| SCHEMBL20024233 | 0.93 | L3MBTL1 (0.40) | KDM4EATML3MBTL1NPY5RSMN1; SMN2 | |
| SCHEMBL20024251 | 0.93 | TBK1 (0.35) | KDM4EATML3MBTL1NPY5RPTGER4 | |
| SCHEMBL20030007 | 0.91 | L3MBTL1 (0.39) | KDM4EATML3MBTL1NPY5RSMN1; SMN2 | |
| SCHEMBL20030001 | 0.90 | KDM4E (0.35) | KDM4EATML3MBTL1NPY5RSMN1; SMN2 | |
| SCHEMBL30929924 | 0.89 | L3MBTL1 (0.39) | KDM4EATML3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL21176405 | 0.89 | L3MBTL1 (0.39) | KDM4EATML3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL20030004 | 0.87 | SMN1; SMN2 (0.34) | KDM4EATML3MBTL1NPY5RSMN1; SMN2 | |
| SCHEMBL19887608 | 0.87 | TBK1 (0.35) | KDM4EATML3MBTL1NPY5RPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3519415-B1 | CARBAZOLES WITH DIAZADIBENZOFURANE OR DIAZADIBENZOTHIOPHENE STRUCTURES | MERCK PATENT GMBH (DE) | 2022-12-14 | — | — | EP | disclosed |
| WO-2018060218-A1 | CARBAZOLES WITH DIAZADIBENZOFURANE OR DIAZADIBENZOTHIOPHENE STRUCTURES | MERCK PATENT GMBH (DE) | 2018-04-05 | — | — | WO | disclosed |