Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | DHODH | Q02127 | 2/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | AKT2 | P31751 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3926750 | 0.85 | L3MBTL1 (0.69) | L3MBTL1KDM4ELMNATDP1GAA | |
| SCHEMBL3925029 | 0.83 | ALDH1A1 (0.73) | L3MBTL1KDM4ELMNATDP1GAA | |
| SCHEMBL1102420 | 0.81 | KDM4E (0.61) | L3MBTL1KDM4ELMNATDP1GAA | |
| SCHEMBL13950894 | 0.77 | KDM4E (0.78) | L3MBTL1KDM4ELMNATDP1GAA | |
| SCHEMBL28224205 | 0.77 | RAB9A (0.47) | L3MBTL1KDM4EDHODHPDE10AMAPT | |
| SCHEMBL31010873 | 0.76 | NPC1 (0.67) | L3MBTL1KDM4EGAADHODHMAPT | |
| SCHEMBL4605644 | 0.76 | KMT2A (0.64) | L3MBTL1KDM4ELMNATDP1GAA | |
| SCHEMBL6341547 | 0.76 | TDP1 (0.91) | L3MBTL1KDM4ELMNATDP1GAA | |
| SCHEMBL8016751 | 0.76 | L3MBTL1 (0.91) | L3MBTL1KDM4ELMNATDP1GAA | |
| SCHEMBL24590007 | 0.75 | KDM4E (0.75) | L3MBTL1KDM4ELMNATDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180093252-A1 | POROUS CYCLODEXTRIN POLYMERIC MATERIALS AND METHODS OF MAKING AND USING SAME | NATIONAL SCIENCE FOUNDATION | 2018-04-05 | — | — | US | disclosed |