SCHEMBL2002804

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2004134	0.94	SMN1; SMN2 (0.40)	NPC1RAB9ASMN1; SMN2MAPTKMT2A
	SCHEMBL2002872	0.93	PLA2G2A (0.49)	NPC1RAB9ASMN1; SMN2PLA2G2APKM
	SCHEMBL2003066	0.92	MAPT (0.46)	SMN1; SMN2PLA2G2APKMMAPTKMT2A
	SCHEMBL2006770	0.92	GRM5 (0.42)	NPC1RAB9ASMN1; SMN2PKMMAPT
	SCHEMBL2001691	0.91	NPC1 (0.41)	NPC1RAB9ASMN1; SMN2PLA2G2APKM
	SCHEMBL2004420	0.90	FAAH (0.44)	NPC1RAB9ASMN1; SMN2PKMMAPT
	SCHEMBL2005119	0.89	MAPT (0.43)	PLA2G2APKMMAPTKMT2ALMNA
	SCHEMBL2002568	0.89	PKM (0.43)	NPC1RAB9APLA2G2APKMMAPT
	SCHEMBL2000418	0.89	MEN1 (0.43)	PLA2G2APKMMAPTKMT2ALMNA
	SCHEMBL2003750	0.89	FAAH (0.40)	NPC1RAB9ASMN1; SMN2PKMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.