Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL27474233 | 0.86 | ALDH1A1 (0.65) | ALDH1A1RXFP1SMN1; SMN2ADORA2BTSHR | |
| SCHEMBL684300 | 0.84 | ALDH1A1 (0.55) | ALDH1A1RXFP1SMN1; SMN2ADORA2BTSHR | |
| SCHEMBL10113917 | 0.83 | RXFP1 (0.68) | ALDH1A1RXFP1SMN1; SMN2TSHRTP53 | |
| SCHEMBL10966452 | 0.79 | RXFP1 (0.64) | ALDH1A1RXFP1SMN1; SMN2ADORA2BTSHR | |
| SCHEMBL18166647 | 0.79 | CYP1A2 (0.66) | ALDH1A1RXFP1SMN1; SMN2ADORA2BTSHR | |
| SCHEMBL18166669 | 0.78 | ALDH1A1 (0.61) | ALDH1A1RXFP1SMN1; SMN2ADORA2BTSHR | |
| SCHEMBL684304 | 0.78 | RXFP1 (0.55) | ALDH1A1RXFP1SMN1; SMN2ADORA2BTSHR | |
| SCHEMBL10500751 | 0.78 | ALDH1A1 (0.71) | ALDH1A1RXFP1SMN1; SMN2ADORA2BTSHR | |
| SCHEMBL7141074 | 0.78 | RXFP1 (0.73) | ALDH1A1RXFP1SMN1; SMN2ADORA2BTSHR | |
| SCHEMBL684309 | 0.78 | ALDH1A1 (0.50) | ALDH1A1RXFP1SMN1; SMN2ADORA2BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10351567-B2 | Methods and compositions for treating pain | ELI LILLY AND COMPANY (US) | 2019-07-16 | — | — | US | disclosed |
| US-20180093986-A1 | METHODS AND COMPOSITIONS FOR TREATING PAIN | HYDRA BIOSCIENCES, INC. (US) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10351567-B2 | Methods and compositions for treating pain | ACHE, COL2A1, MMP8 | ALDH1A1 540/4885RXFP1 611/4885SMN1; SMN2 365/4885 |
| US-20180093986-A1 | METHODS AND COMPOSITIONS FOR TREATING PAIN | ACHE, COL2A1, MMP8 | ALDH1A1 540/4885RXFP1 611/4885SMN1; SMN2 365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.