Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | UBE2M | P61081 | 1/20 | 0.46 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11143056 | 0.82 | ALDH1A1 (0.58) | LMNAPTGESNPSR1SOAT2SOAT1 | |
| SCHEMBL6899771 | 0.79 | SOAT1 (0.62) | LMNASOAT2SOAT1KMT2AUBE2M | |
| SCHEMBL9723419 | 0.78 | SOAT2 (0.51) | LMNAPTGESNPSR1SOAT2SOAT1 | |
| SCHEMBL9678916 | 0.78 | MEN1 (0.47) | POLBLMNAGAANPSR1SOAT2 | |
| SCHEMBL9681145 | 0.77 | SOAT2 (0.56) | LMNASOAT2SOAT1KMT2A | |
| SCHEMBL9765025 | 0.76 | SOAT2 (0.49) | LMNANPSR1SOAT2SOAT1KMT2A | |
| SCHEMBL9679656 | 0.74 | SOAT2 (0.60) | LMNASOAT2SOAT1KMT2A | |
| SCHEMBL9679390 | 0.74 | ALDH1A1 (0.58) | POLBLMNANPSR1SOAT2SOAT1 | |
| SCHEMBL9844078 | 0.74 | SOAT1 (0.56) | LMNASOAT2SOAT1KMT2A | |
| SCHEMBL5463525 | 0.74 | LMNA (0.81) | LMNAGAANPSR1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10968297-B2 | Thiourea group IV transition metal catalysts and polymerization systems | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-04-06 | — | — | US | disclosed |
| EP-3519464-B1 | THIOUREA GROUP IV TRANSITION METAL CATALYSTS AND POLYMERIZATION SYSTEMS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-08-19 | — | — | EP | disclosed |
| US-20190202950-A1 | THIOUREA GROUP IV TRANSITION METAL CATALYSTS AND POLYMERIZATION SYSTEMS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-07-04 | — | — | US | disclosed |
| WO-2018063799-A1 | THIOUREA GROUP IV TRANSITION METAL CATALYSTS AND POLYMERIZATION SYSTEMS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10968297-B2 | Thiourea group IV transition metal catalysts and polymerization systems | TTI1, TST, TTI2 | POLB 614/4885LMNA 4484/4885GAA 2242/4885 |
| US-20190202950-A1 | THIOUREA GROUP IV TRANSITION METAL CATALYSTS AND POLYMERIZATION SYSTEMS | TTI1, TST, TTI2 | POLB 614/4885LMNA 4484/4885GAA 2242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.