Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LY96 | Q9Y6Y9 | 2/20 | 0.38 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10687435 | 0.88 | LMNA (0.53) | ALDH1A1THRBLMNAKMT2AMAPK1 | |
| SCHEMBL6324521 | 0.88 | LMNA (0.53) | ALDH1A1THRBLMNAKMT2AMAPK1 | |
| SCHEMBL6324514 | 0.88 | LMNA (0.53) | ALDH1A1THRBLMNAKMT2AMAPK1 | |
| SCHEMBL19767509 | 0.87 | LMNA (0.60) | ALDH1A1THRBLMNAKMT2APOLB | |
| SCHEMBL15333945 | 0.87 | LMNA (0.60) | ALDH1A1THRBLMNAKMT2APOLB | |
| SCHEMBL23046595 | 0.87 | LMNA (0.60) | ALDH1A1THRBLMNAKMT2APOLB | |
| SCHEMBL16882358 | 0.87 | LMNA (0.60) | ALDH1A1THRBLMNAKMT2APOLB | |
| SCHEMBL18710677 | 0.87 | LMNA (0.60) | ALDH1A1THRBLMNAKMT2APOLB | |
| SCHEMBL24219925 | 0.87 | LMNA (0.60) | ALDH1A1THRBLMNAKMT2APOLB | |
| SCHEMBL15344529 | 0.87 | LMNA (0.60) | ALDH1A1THRBLMNAKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180094017-A1 | OLIGONUCLEOTIDE DERIVATIVE, OLIGONUCLEOTIDE CONSTRUCT USING THE SAME, AND METHODS FOR PRODUCING THEM | GIFU UNIVERSITY (JP) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180094017-A1 | OLIGONUCLEOTIDE DERIVATIVE, OLIGONUCLEOTIDE CONSTRUCT USING THE SAME, AND METHODS FOR PRODUCING THEM | APOB, TTPA, AOX1 | ALDH1A1 603/4885THRB 1819/4885LMNA 717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.