Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TLR4 | O00206 | 5/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LY96 | Q9Y6Y9 | 2/20 | 0.41 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.41 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.41 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.41 |
| ▸ | CD69 | Q07108 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10687435 | 1.00 | LMNA (0.53) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL6324521 | 1.00 | LMNA (0.53) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL24699769 | 0.91 | LMNA (0.48) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL7154645 | 0.88 | ALDH1A1 (0.52) | LMNAKMT2AALDH1A1POLBTHRB | |
| SCHEMBL7154639 | 0.88 | ALDH1A1 (0.52) | LMNAKMT2AALDH1A1POLBTHRB | |
| SCHEMBL8027243 | 0.88 | ALDH1A1 (0.52) | LMNAKMT2AALDH1A1POLBTHRB | |
| SCHEMBL29556423 | 0.88 | ALDH1A1 (0.52) | LMNAKMT2AALDH1A1POLBTHRB | |
| SCHEMBL20032351 | 0.88 | ALDH1A1 (0.52) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL8023508 | 0.87 | LMNA (0.45) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL8023515 | 0.87 | LMNA (0.45) | LMNAKMT2AALDH1A1POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6858724-B2 | Non-mucin type synthetic compounds or its carrier conjugated compounds | KOTOBUKI PHARMACEUTICAL CO., LTD. (JP) | 2005-02-22 | — | — | US | disclosed |
| US-20020107224-A1 | Non-mucin type synthetic compounds or its carrier conjugated compounds | KOTOBUKI PHARMACEUTICAL CO., LTD. (JP) | 2002-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107224-A1 | Non-mucin type synthetic compounds or its carrier conjugated compounds | MUC1, FUT5, ST6GAL1 | LMNA 4472/4885KMT2A 2303/4885ALDH1A1 455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.