SCHEMBL2003352

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2009542	0.89	ALDH1A1 (0.50)	ALDH1A1SMN1; SMN2L3MBTL1HDAC3HDAC4
	SCHEMBL2006326	0.89	ALDH1A1 (0.50)	ALDH1A1SMN1; SMN2L3MBTL1HDAC3HDAC4
	SCHEMBL2010721	0.89	PKM (0.51)	ALDH1A1SMN1; SMN2L3MBTL1HDAC3HDAC4
	SCHEMBL8200985	0.89	RAB9A (0.49)	SMN1; SMN2HDAC3HDAC4HDAC1HDAC7
	SCHEMBL2005153	0.89	PKM (0.54)	ALDH1A1SMN1; SMN2L3MBTL1HDAC3HDAC4
	SCHEMBL13270639	0.87	KMT2A (0.48)	ALDH1A1SMN1; SMN2LMNAMEN1TSHR
	SCHEMBL1021267	0.87	MAPT (0.52)	ALDH1A1SMN1; SMN2L3MBTL1PKMHPGD
	SCHEMBL2012534	0.87	HSD11B1 (0.59)	ALDH1A1SMN1; SMN2L3MBTL1PKMLMNA
	SCHEMBL2012800	0.85	NPC1 (0.52)	ALDH1A1SMN1; SMN2L3MBTL1PKMLMNA
	SCHEMBL14555299	0.85	HDAC3 (0.50)	ALDH1A1SMN1; SMN2L3MBTL1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.