SCHEMBL2005153

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2006326	0.89	ALDH1A1 (0.50)	PKMALDH1A1HPGDSMN1; SMN2L3MBTL1
	SCHEMBL2009542	0.89	ALDH1A1 (0.50)	PKMALDH1A1HPGDSMN1; SMN2L3MBTL1
	SCHEMBL2010721	0.89	PKM (0.51)	PKMALDH1A1HPGDSMN1; SMN2L3MBTL1
	SCHEMBL2003352	0.89	ALDH1A1 (0.50)	PKMALDH1A1HPGDSMN1; SMN2L3MBTL1
	SCHEMBL8200985	0.89	RAB9A (0.49)	PKMSMN1; SMN2RAB9ALMNAKDM4E
	SCHEMBL1021267	0.86	MAPT (0.52)	PKMALDH1A1HPGDSMN1; SMN2L3MBTL1
	SCHEMBL2012534	0.86	HSD11B1 (0.59)	PKMALDH1A1SMN1; SMN2L3MBTL1LMNA
	SCHEMBL2003957	0.85	MAPT (0.56)	PKMALDH1A1LMNAGBA1MEN1
	SCHEMBL2012800	0.85	NPC1 (0.52)	PKMALDH1A1SMN1; SMN2L3MBTL1RAB9A
	SCHEMBL14555299	0.85	HDAC3 (0.50)	PKMALDH1A1HPGDSMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.