SCHEMBL20036428

SCHEMBL20036428

Cc1ccc2c(n1)oc1c(-c3cc(Cl)c(C)cn3)cccc12

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 1/20 0.35
CRHR1 P34998 3/20 0.33
MAPT P10636 2/20 0.31
USP2 O75604 1/20 0.31
POLB P06746 1/20 0.31
TSHR P16473 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31671134 1.00 ADORA1 (0.35) ADORA1CRHR1MAPTUSP2POLB
SCHEMBL20036429 0.91 CRHR1 (0.33) ADORA1CRHR1MAPTUSP2POLB
SCHEMBL25774845 0.85 KCNA3 (0.37) ADORA1CRHR1
SCHEMBL31671133 0.85 KCNA3 (0.37) ADORA1CRHR1
SCHEMBL20457179 0.84 LMNA (0.32)
SCHEMBL20044914 0.83 NPC1 (0.34)
SCHEMBL20457178 0.82 AAK1 (0.33)
SCHEMBL25761835 0.82 MAOB (0.36)
SCHEMBL18604409 0.82 CRHR1 (0.34) CRHR1MAPTPOLB
SCHEMBL23785417 0.81 KCNA3 (0.37) ADORA1CRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118165040-A Organic electroluminescent material and device 环球展览公司 2024-06-11 CN disclosed
CN-118165039-A Organic electroluminescent material and device 环球展览公司 2024-06-11 CN disclosed
US-20230309378-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 US disclosed
US-20230309378-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 US disclosed
US-11711968-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-25 US disclosed
US-11711968-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-25 US disclosed
US-20220399510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-12-15 US disclosed
EP-3858844-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2021-08-04 EP disclosed
US-11011709-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-05-18 US disclosed
EP-3305796-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2021-03-31 EP disclosed
US-20180102487-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-04-12 US disclosed
US-20180102487-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-04-12 US disclosed
EP-3305796-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2018-04-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11011709-B2 Organic electroluminescent materials and devices OCIAD1, RPS8, LMNB1 ADORA1 2173/4885CRHR1 2650/4885MAPT 3133/4885
US-11711968-B2 Organic electroluminescent materials and devices OCIAD1, LMNB1, RPS8 ADORA1 2188/4885CRHR1 2638/4885MAPT 3147/4885
US-20180102487-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, LMNB1, RPS8 ADORA1 2188/4885CRHR1 2638/4885MAPT 3147/4885
US-20220399510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, KCNH3, KCNH2 ADORA1 1800/4885CRHR1 2630/4885MAPT 4386/4885
US-20230309378-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, LMNB1, RPS8 ADORA1 2188/4885CRHR1 2638/4885MAPT 3147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.