SCHEMBL2003785

SCHEMBL2003785

Cc1ccccc1N=NNc1ccccc1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.49
GRIN2D O15399 4/20 0.47
GRIN3B O60391 4/20 0.47
GRIN1 Q05586 4/20 0.47
GRIN2A Q12879 4/20 0.47
GRIN2B Q13224 4/20 0.47
GRIN2C Q14957 4/20 0.47
GRIN3A Q8TCU5 4/20 0.47
TSHR P16473 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
PABPC1 P11940 1/20 0.47
ALOX15 P16050 1/20 0.47
EBP Q15125 1/20 0.47
TMEM97 Q5BJF2 1/20 0.47
MAPT P10636 5/20 0.42
HTT P42858 1/20 0.42
HPGD P15428 5/20 0.42
ALDH1A1 P00352 5/20 0.42
TDP1 Q9NUW8 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24133230 1.00 SIGMAR1 (0.49) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL29074603 0.83 TRPA1 (0.45) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL29664063 0.83 MAPT (0.52) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL11295615 0.79 TSHR (0.48) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL11210126 0.77 MAPT (0.43) TSHRMEN1KMT2AMAPTHTT
SCHEMBL11290782 0.77 KEAP1 (0.42) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL11015269 0.77 MAPT (0.43) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL10519325 0.77 MAPT (0.46) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL13241362 0.77 CYP2C9 (0.44) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL9597558 0.77 CYP2C9 (0.44) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4076940-B1 A SEALING DEVICE WITH HIGH SURFACE ROUGHNESS SIKA TECH AG (CH) 2025-06-04 EP claimed
CN-114728494-B Sealing device with high surface roughness SIKA技术股份公司 2024-12-31 CN claimed
US-12163588-B2 Sealing device with increased surface roughness SIKA TECHNOLOGY AG (CH) 2024-12-10 US claimed
US-20230399779-A1 Polymeric Non-Woven Mat America Plastics, LLC (US) 2023-12-14 US claimed
US-20220396056-A1 A SEALING DEVICE WITH INCREASED SURFACE ROUGHNESS SIKA TECHNOLOGY AG (CH) 2022-12-15 US claimed
EP-4076940-A1 A SEALING DEVICE WITH HIGH SURFACE ROUGHNESS Sika Technology AG (CH) 2022-10-26 EP claimed
CN-114728494-A Sealing device with high surface roughness SIKA技术股份公司 2022-07-08 CN claimed
US-12552140-B2 Sealing device with increased concrete adhesion strength SIKA TECHNOLOGY AG (CH) 2026-02-17 US disclosed
US-12509879-B2 Fully bonded single-layer waterbar SIKA TECHNOLOGY AG (CH) 2025-12-30 US disclosed
US-12343964-B2 Waterproofing membrane with a solid filler component SIKA TECHNOLOGY AG (CH) 2025-07-01 US disclosed
EP-4168637-B1 PROCESS FOR PRODUCING A FULLY BONDED SINGLE-LAYER WATERBAR SIKA TECH AG (CH) 2025-06-11 EP disclosed
EP-4076940-B1 A SEALING DEVICE WITH HIGH SURFACE ROUGHNESS SIKA TECH AG (CH) 2025-06-04 EP disclosed
US-20250101265-A1 THIN FILM SEALING DEVICE WITH IMPROVED ADHESION TO CONCRETE SIKA TECHNOLOGY AG (CH) 2025-03-27 US disclosed
EP-0013643-B1 PRODUCTION OF HIGH-QUALITY AROMATIC AMINO AZO COMPOUNDS BY THE REARRANGEMENT OF 1,3-DIARYL TRIAZENES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-12-08 EP disclosed
US-4279815-A DIAZOTIZATION, COUPLING HERKES FRANK E 1981-07-21 US disclosed
EP-0013643-A1 Production of high-quality aromatic amino azo compounds by the rearrangement of 1,3-diaryl triazenes E.I. DU PONT DE NEMOURS AND COMPANY (US) 1980-07-23 EP disclosed
US-4089850-A FOR METAL MODIFIED POLYPROPYLENE AMERICAN COLOR & CHEMICAL CORPORATION (US) 1978-05-16 US disclosed
US-4066388-A DISAZO DYES DERIVED FROM 1-ACYL-2,4-DIHYDROXYBENZENES AND METALLIZED POLYOLEFIN DYED THEREWITH AMERICAN COLOR & CHEMICAL CORPORATION (US) 1978-01-03 US disclosed
US-4017245-A Apparatus for extruding expandable thermoplastic material FOSTER GRANT CO., INC. (US) 1977-04-12 US disclosed
US-4012193-A Bisazomethine dyes for metal-modified polyolefins AMERICAN COLOR & CHEMICAL CORPORATION (US) 1977-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509879-B2 Fully bonded single-layer waterbar AQP1, GZMB, GJB2 SIGMAR1 2898/4885GRIN2D 505/4885GRIN3B 1595/4885
US-12552140-B2 Sealing device with increased concrete adhesion strength ICAM1, TLN1, CAPZA2 SIGMAR1 3508/4885GRIN2D 231/4885GRIN3B 3599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.