Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18291559 | 0.81 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2POLBMAPTHDAC3 | |
| SCHEMBL18291746 | 0.80 | GABRP (0.53) | ALDH1A1SMN1; SMN2POLBMAPTHDAC3 | |
| SCHEMBL14007030 | 0.80 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2POLBMAPTRAB9A | |
| SCHEMBL4163162 | 0.78 | CHRNB2 (0.47) | ALDH1A1POLB | |
| SCHEMBL20249193 | 0.78 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2POLBMAPTHDAC3 | |
| SCHEMBL31707298 | 0.77 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2POLBMAPTHDAC3 | |
| SCHEMBL238472 | 0.76 | — | — | |
| SCHEMBL238473 | 0.76 | — | — | |
| SCHEMBL10062422 | 0.75 | PLAU (0.30) | — | |
| SCHEMBL12010848 | 0.74 | HCAR3 (0.43) | ALDH1A1SMN1; SMN2POLBMAPTHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |