Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | PRLHR | P49683 | 4/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042719 | 0.81 | HSD17B10 (0.46) | PROKR1KMT2AHSD17B10MGLLMAPT | |
| SCHEMBL20042749 | 0.71 | PKM (0.43) | KMT2AMAPTPOLB | |
| SCHEMBL20042862 | 0.71 | HPGD (0.48) | KMT2AMAPT | |
| SCHEMBL20042795 | 0.70 | HPGD (0.46) | PDE10A | |
| SCHEMBL20042722 | 0.70 | ALDH1A1 (0.43) | KMT2AMGLL | |
| SCHEMBL20042751 | 0.68 | HSD17B10 (0.49) | KMT2AHSD17B10MGLLPOLB | |
| SCHEMBL20042980 | 0.68 | LSS (0.50) | KMT2AHSD17B10PRLHRMAPTPOLB | |
| SCHEMBL20042920 | 0.68 | GRM5 (0.41) | PROKR1MGLL | |
| SCHEMBL20042687 | 0.68 | HSD17B10 (0.51) | KMT2AHSD17B10MGLLMAPTPOLB | |
| SCHEMBL20042725 | 0.67 | PDE2A (0.41) | PROKR1MGLLPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |