Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | PRLHR | P49683 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 2/20 | 0.40 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.39 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042728 | 0.88 | MEN1 (0.42) | MEN1KMT2AL3MBTL1PDE2ASLC6A7 | |
| SCHEMBL20043028 | 0.87 | KDM4E (0.40) | GRM5P2RX7MEN1KMT2AL3MBTL1 | |
| SCHEMBL20042668 | 0.86 | HPGD (0.51) | GRM5P2RX7MEN1KMT2AL3MBTL1 | |
| SCHEMBL20042713 | 0.85 | GRM5 (0.45) | GRM5P2RX7MEN1KMT2AL3MBTL1 | |
| SCHEMBL20042656 | 0.85 | KDM4E (0.37) | GRM5P2RX7MEN1KMT2AL3MBTL1 | |
| SCHEMBL20042903 | 0.85 | MEN1 (0.42) | P2RX7MEN1KMT2AL3MBTL1CFTR | |
| SCHEMBL20042684 | 0.85 | SMN1; SMN2 (0.52) | GRM5P2RX7 | |
| SCHEMBL20042771 | 0.85 | P2RX7 (0.47) | GRM5P2RX7MEN1KMT2AL3MBTL1 | |
| SCHEMBL20042839 | 0.84 | P2RX7 (0.45) | P2RX7SMOMEN1KMT2AL3MBTL1 | |
| SCHEMBL20042754 | 0.83 | MEN1 (0.41) | GRM5P2RX7MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |