Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.47 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042744 | 0.86 | MTHFD2 (0.44) | P2RX7MTHFD2KIF11HPGDGRM5 | |
| SCHEMBL20042839 | 0.81 | P2RX7 (0.45) | P2RX7MTHFD2HPGDALDH1A1TSHR | |
| SCHEMBL20042730 | 0.78 | NPC1 (0.48) | P2RX7HPGDALDH1A1TSHR | |
| SCHEMBL20042726 | 0.77 | PKM (0.45) | P2RX7GRM5ALDH1A1 | |
| SCHEMBL20042749 | 0.74 | PKM (0.43) | P2RX7HPGDGRM5ALDH1A1 | |
| SCHEMBL25342146 | 0.74 | MEN1 (0.44) | P2RX7MTHFD2LMNATSHR | |
| SCHEMBL20042664 | 0.74 | P2RX7 (0.40) | P2RX7 | |
| SCHEMBL20042751 | 0.74 | HSD17B10 (0.49) | P2RX7HPGDALDH1A1LMNA | |
| SCHEMBL20042771 | 0.73 | P2RX7 (0.47) | P2RX7HPGDGRM5ALDH1A1LMNA | |
| SCHEMBL11400880 | 0.71 | PTGS1 (0.50) | MTHFD2KIF11GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |