SCHEMBL200490

SCHEMBL200490

CC1(COC(=O)c2c3ccccc3cc3ccccc23)CC2C=CC1C2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.39
ALDH1A1 P00352 4/20 0.39
HPGD P15428 4/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
GLA P06280 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
ATM Q13315 1/20 0.38
HSD17B10 Q99714 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35
P2RX7 Q99572 1/20 0.34
POLB P06746 1/20 0.32
EPHX1 P07099 1/20 0.32
ABCB1 P08183 7/20 0.32
ABCG2 Q9UNQ0 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL202759 0.84 CDC25B (0.46) KDM4EALDH1A1HPGDKMT2AMAPT
SCHEMBL200989 0.82 HRH3 (0.44) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL2892925 0.80 ALDH1A1 (0.38) KDM4EALDH1A1HPGDL3MBTL1MEN1
SCHEMBL200205 0.77 KDM4E (0.43) KDM4EALDH1A1MEN1KMT2ACYP1A2
SCHEMBL202552 0.75 SCN1A (0.44) MEN1KMT2ALMNA
SCHEMBL5835576 0.71 CA12 (0.55) KDM4EALDH1A1HPGDL3MBTL1MEN1
SCHEMBL5355018 0.71 CYP2D6 (0.35) CYP2C19P2RX7
SCHEMBL5358484 0.70 ALDH1A1 (0.38) ALDH1A1LMNACYP2C19
SCHEMBL200050 0.69 KDM4E (0.42) KDM4EALDH1A1HPGDL3MBTL1MEN1
SCHEMBL5348568 0.68 CYP2D6 (0.35) CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9417477-B2 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2016-08-16 US disclosed
US-20150146140-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-05-28 US disclosed
US-8089593-B2 Optical resin film, optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2012-01-03 US disclosed
US-7719644-B2 Optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2010-05-18 US disclosed
US-20090033835-A1 Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2009-02-05 US disclosed
US-20080284957-A1 Optical Resin Film, Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
WO-2006082818-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2006-08-10 WO disclosed
US-7008569-B2 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2006-03-07 US disclosed
US-20040057141-A1 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2004-03-25 US disclosed
EP-1395855-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR Corporation (JP) 2004-03-10 EP disclosed
WO-2002088784-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR CORPORATION (JP) 2002-11-07 WO disclosed