⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25583605 | 0.82 | NOS3 (0.39) | — | |
| SCHEMBL25587712 | 0.73 | GRIN2B (0.40) | — | |
| SCHEMBL25584224 | 0.71 | GRIN2B (0.40) | — | |
| SCHEMBL25587614 | 0.71 | GRIN2B (0.42) | — | |
| SCHEMBL20049966 | 0.70 | GRIN2B (0.43) | — | |
| SCHEMBL25587000 | 0.70 | GRIN2B (0.43) | — | |
| SCHEMBL20049785 | 0.70 | GPBAR1 (0.39) | — | |
| SCHEMBL25584017 | 0.70 | GRIN2B (0.40) | — | |
| SCHEMBL25584270 | 0.70 | GRIN2B (0.43) | — | |
| SCHEMBL25587638 | 0.69 | ESR2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018067786-A1 | SUBSTITUTED 1H-IMIDAZO[4,5-B]PYRIDIN-2(3H)-ONES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-04-12 | — | — | WO | disclosed |