Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.35 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20053578 | 0.95 | APEX1 (0.35) | CCKBRAPEX1ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL20053526 | 0.93 | ALDH1A1 (0.37) | CCKBRAPEX1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL20053529 | 0.85 | APEX1 (0.37) | APEX1ALDH1A1MEN1KMT2APTPN7 | |
| SCHEMBL17830705 | 0.82 | APEX1 (0.61) | APEX1MEN1KMT2AMAPTPTPN7 | |
| SCHEMBL20053545 | 0.79 | EP300 (0.40) | ALDH1A1MEN1KMT2APTPN7CACNA1B | |
| SCHEMBL17832352 | 0.77 | APEX1 (0.57) | APEX1MEN1KMT2AMAPTPTPN7 | |
| SCHEMBL17830794 | 0.77 | CCKBR (0.38) | CCKBRAPEX1ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL17830698 | 0.77 | APEX1 (0.57) | APEX1MEN1KMT2AMAPTPTPN7 | |
| SCHEMBL17830710 | 0.75 | ALDH1A1 (0.64) | CCKBRALDH1A1ALDH2ALDH3A1KMT2A | |
| SCHEMBL17830695 | 0.75 | KAT2B (0.54) | APEX1MEN1KMT2AMAPTPTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943506-B2 | BCL6 inhibitors as anticancer agents | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |