Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | EP300 | Q09472 | 2/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.37 |
| ▸ | KAT2A | Q92830 | 2/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20053515 | 0.93 | CCKBR (0.39) | ALDH1A1APEX1CCKBRSMN1; SMN2L3MBTL1 | |
| SCHEMBL20053578 | 0.90 | APEX1 (0.35) | ALDH1A1FFAR1FFAR4MDM2KDM4E | |
| SCHEMBL17830695 | 0.83 | KAT2B (0.54) | EP300CREBBPKAT2AKAT2BAPEX1 | |
| SCHEMBL20053529 | 0.81 | APEX1 (0.37) | ALDH1A1MDM2KDM4EAPEX1HPGD | |
| SCHEMBL20053545 | 0.81 | EP300 (0.40) | ALDH1A1EP300CREBBPKAT2AKAT2B | |
| SCHEMBL17830797 | 0.78 | ALDH1A1 (0.37) | ALDH1A1EP300CREBBPKAT2AKAT2B | |
| SCHEMBL17832352 | 0.77 | APEX1 (0.57) | EP300CREBBPKAT2AKAT2BAPEX1 | |
| SCHEMBL17830742 | 0.75 | ALDH1A1 (0.63) | ALDH1A1GAASMN1; SMN2LMNAMAPT | |
| SCHEMBL17830693 | 0.75 | PTPN7 (0.60) | ALDH1A1EP300CREBBPKAT2AKAT2B | |
| SCHEMBL17830705 | 0.75 | APEX1 (0.61) | EP300CREBBPKAT2AKAT2BAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943506-B2 | BCL6 inhibitors as anticancer agents | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |