Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 3/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20053515 | 0.95 | CCKBR (0.39) | APEX1CCKBRALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL20053526 | 0.90 | ALDH1A1 (0.37) | APEX1CCKBRALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL17830698 | 0.82 | APEX1 (0.57) | APEX1MAPTMEN1KMT2A | |
| SCHEMBL20053529 | 0.82 | APEX1 (0.37) | APEX1ALDH1A1MDM2MEN1KMT2A | |
| SCHEMBL17830705 | 0.77 | APEX1 (0.61) | APEX1MAPTMEN1KMT2A | |
| SCHEMBL17830700 | 0.77 | MEN1 (0.55) | APEX1MAPTMEN1KMT2A | |
| SCHEMBL20053545 | 0.77 | EP300 (0.40) | ALDH1A1FFAR1FFAR4MDM2MEN1 | |
| SCHEMBL17830696 | 0.77 | APEX1 (0.54) | APEX1MAPTMEN1KMT2A | |
| SCHEMBL17830694 | 0.75 | PTPN7 (0.56) | APEX1MAPTMEN1KMT2A | |
| SCHEMBL17830745 | 0.75 | ALDH1A1 (0.56) | ALDH1A1ALDH2ALDH3A1MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943506-B2 | BCL6 inhibitors as anticancer agents | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |