Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16366716 | 0.83 | KAT2B (0.57) | EP300CREBBPKAT2AKAT2BPTPN7 | |
| SCHEMBL20053526 | 0.81 | ALDH1A1 (0.37) | EP300CREBBPKAT2AKAT2BPTPN7 | |
| SCHEMBL20053515 | 0.79 | CCKBR (0.39) | PTPN7CACNA1BAPBA1APOBEC3GPTPN22 | |
| SCHEMBL20053578 | 0.77 | APEX1 (0.35) | KDM4EHPGDMDM2FFAR1ALDH1A1 | |
| SCHEMBL16366700 | 0.75 | CHRM5 (0.53) | CHRM5ALDH1A1MEN1KMT2APARK7 | |
| SCHEMBL20053529 | 0.74 | APEX1 (0.37) | PTPN7CACNA1BAPBA1APOBEC3GPTPN22 | |
| SCHEMBL17830693 | 0.71 | PTPN7 (0.60) | EP300CREBBPKAT2AKAT2BPTPN7 | |
| SCHEMBL17830758 | 0.65 | ALDH3A1 (0.54) | CHRM5ALDH1A1MEN1KMT2A | |
| SCHEMBL17830694 | 0.64 | PTPN7 (0.56) | EP300CREBBPKAT2AKAT2BPTPN7 | |
| SCHEMBL17832352 | 0.64 | APEX1 (0.57) | EP300CREBBPKAT2AKAT2BPTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943506-B2 | BCL6 inhibitors as anticancer agents | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |