Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.35 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 8/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20053515 | 0.85 | CCKBR (0.39) | APEX1ALDH1A1PTPN7CACNA1BAPBA1 | |
| SCHEMBL17830701 | 0.83 | APEX1 (0.58) | APEX1PTPN7CACNA1BAPBA1PTPN22 | |
| SCHEMBL20053578 | 0.82 | APEX1 (0.35) | APEX1ALDH1A1MDM2MEN1KMT2A | |
| SCHEMBL20053526 | 0.81 | ALDH1A1 (0.37) | APEX1ALDH1A1PTPN7CACNA1BAPBA1 | |
| SCHEMBL17830800 | 0.78 | RECQL (0.36) | APEX1RECQLALDH1A1AGTR1PTPN7 | |
| SCHEMBL17830750 | 0.76 | ALDH1A1 (0.57) | RECQLALDH1A1AGTR1MEN1KMT2A | |
| SCHEMBL20053545 | 0.74 | EP300 (0.40) | ALDH1A1PTPN7CACNA1BAPBA1PTPN22 | |
| SCHEMBL17830704 | 0.68 | APEX1 (0.61) | APEX1PTPN7CACNA1BAPBA1PTPN22 | |
| SCHEMBL17830705 | 0.67 | APEX1 (0.61) | APEX1PTPN7CACNA1BAPBA1PTPN22 | |
| SCHEMBL17830698 | 0.64 | APEX1 (0.57) | APEX1PTPN7CACNA1BAPBA1PTPN22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943506-B2 | BCL6 inhibitors as anticancer agents | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |