Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20054582 | 0.79 | SHBG (0.40) | PDE10A | |
| SCHEMBL20054474 | 0.72 | PDE10A (0.32) | PDE10A | |
| SCHEMBL20054552 | 0.67 | NLN (0.43) | PDE10A | |
| SCHEMBL12965884 | 0.64 | CHRNB2 (0.39) | — | |
| SCHEMBL20055405 | 0.61 | TRPV1 (0.46) | PDE10A | |
| SCHEMBL1408151 | 0.60 | LOXL2 (0.37) | PDE10A | |
| SCHEMBL20054554 | 0.60 | AAK1 (0.46) | PDE10A | |
| SCHEMBL17066706 | 0.59 | MAOB (0.43) | PDE10ANPC1RAB9A | |
| SCHEMBL16177862 | 0.59 | — | — | |
| SCHEMBL20054467 | 0.57 | PDE10A (0.40) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019196-B1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-2802326-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-18 | — | — | EP | disclosed |