Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.51 |
| ▸ | ERN1 | O75460 | 1/20 | 0.51 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.46 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CTSA | P10619 | 1/20 | 0.43 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20056401 | 0.83 | ESR2 (0.46) | ESR2TLR8CXCL12 | |
| SCHEMBL2410947 | 0.80 | CA1 (0.61) | ERN1KCNMA1ALDH1A1HPGDAR | |
| SCHEMBL12834087 | 0.80 | ERN1 (0.71) | ERN1KCNMA1KMT2A | |
| SCHEMBL20056483 | 0.79 | ESR2 (0.57) | ESR2TLR8MEN1KMT2A | |
| SCHEMBL10093048 | 0.78 | AGPAT2 (0.57) | ERN1KCNMA1MEN1KMT2AALDH1A1 | |
| SCHEMBL14599496 | 0.78 | HSD17B1 (0.52) | ESR2TLR8MEN1KMT2AKDM4E | |
| SCHEMBL20056607 | 0.78 | KDM1A (0.52) | TLR8CTSAAR | |
| SCHEMBL18155551 | 0.76 | TUBB4A (0.46) | ERN1KCNMA1CXCL12MEN1KMT2A | |
| SCHEMBL14499509 | 0.76 | CYP1A2 (0.45) | KDM4E | |
| SCHEMBL7699644 | 0.75 | ALDH1A1 (0.56) | ERN1MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970353-B1 | MANNOSE DERIVATIVES FOR TREATING BACTERIAL INFECTIONS | VERTEX PHARMA (US) | 2018-04-18 | — | — | EP | disclosed |