Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20060002 | 0.78 | ALDH1A1 (0.42) | LMNASMN1; SMN2GAAMAPTHPGD | |
| SCHEMBL20060196 | 0.78 | CTSD (0.39) | MEN1KMT2ALMNASMN1; SMN2GAA | |
| SCHEMBL20060154 | 0.77 | GLS (0.38) | MEN1KMT2ALMNASMN1; SMN2GAA | |
| SCHEMBL20060005 | 0.74 | — | — | |
| SCHEMBL20060139 | 0.73 | CMA1 (0.39) | MAPTTSHRHPGDTAAR1 | |
| SCHEMBL20060020 | 0.72 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL20060136 | 0.69 | MEN1 (0.37) | MEN1KMT2A | |
| SCHEMBL20060217 | 0.69 | IGF1R (0.55) | — | |
| SCHEMBL20060018 | 0.67 | — | — | |
| SCHEMBL8314477 | 0.67 | MEN1 (0.63) | MEN1KMT2ASMN1; SMN2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595987-B1 | NEW AMINOPYRAZOLOQUINAZOLINES | BOEHRINGER INGELHEIM INT (DE) | 2018-04-18 | — | — | EP | disclosed |