Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 10/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.34 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2006911 | 0.94 | PLA2G2A (0.37) | ALOX5APALOX5F2RL3LMNAMAPT | |
| SCHEMBL2005424 | 0.93 | ALOX5AP (0.42) | ALOX5APALOX5 | |
| SCHEMBL2004795 | 0.92 | MAPT (0.34) | ALOX5APALOX5LMNAMAPT | |
| SCHEMBL2002746 | 0.91 | F2RL3 (0.37) | ALOX5APALOX5F2RL3LMNAMAPT | |
| SCHEMBL2006586 | 0.91 | ALOX5AP (0.39) | ALOX5APALOX5F2RL3SLC26A4POLB | |
| SCHEMBL2005115 | 0.91 | ALOX5AP (0.37) | ALOX5APALOX5SLC26A4POLBLMNA | |
| SCHEMBL2001446 | 0.90 | FAAH (0.35) | ALOX5APALOX5LMNAMAPTSMN1; SMN2 | |
| SCHEMBL2005302 | 0.89 | L3MBTL1 (0.35) | ALOX5APALOX5LMNAMAPT | |
| SCHEMBL2004327 | 0.89 | F2RL3 (0.34) | ALOX5APALOX5F2RL3SLC26A4POLB | |
| SCHEMBL2006087 | 0.88 | LMNA (0.39) | ALOX5APPOLBLMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8884020-B2 | Indole compounds | IRONWOOD PHARMACEUTICALS, INC. (US) | 2014-11-11 | — | — | US | disclosed |
| US-7960544-B2 | Useful indole compounds | IRONWOOD PHARMACEUTICALS, INC. (US) | 2011-06-14 | — | — | US | disclosed |
| US-20100197708-A1 | INDOLE COMPOUNDS | WELLS FARGO BANK, NATIONAL ASSOCIATION | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197708-A1 | INDOLE COMPOUNDS | IDO1, IDO2, TPH2 | ALOX5AP 198/4885ALOX5 120/4885F2RL3 642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.