Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12437171 | 1.00 | RAB9A (0.42) | RAB9ALMNACYP3A4CYP2D6TSHR | |
| SCHEMBL12253305 | 0.87 | MAPT (0.39) | RAB9ALMNAMAPTNPC1KDM4E | |
| SCHEMBL1719023 | 0.84 | ATM (0.42) | RAB9AMAPTNPC1POLBSMN1; SMN2 | |
| SCHEMBL12567258 | 0.79 | RAB9A (0.42) | RAB9ALMNACYP3A4CYP2D6TSHR | |
| SCHEMBL1993959 | 0.78 | LMNA (0.49) | LMNAADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL11903742 | 0.76 | LMNA (0.57) | LMNAADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL12437176 | 0.74 | HTR1D (0.50) | LMNACYP2D6ADRA2AADRA2BADRA2C | |
| SCHEMBL12437177 | 0.74 | HTR1D (0.50) | LMNACYP2D6ADRA2AADRA2BADRA2C | |
| SCHEMBL2214929 | 0.74 | HTR1D (0.50) | LMNACYP2D6ADRA2AADRA2BADRA2C | |
| SCHEMBL2216731 | 0.74 | ADRA2A (0.57) | ADRA2AADRA2BADRA2CADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101855213-B | Therapeutic compounds | ALLERGAN INC | 2014-09-10 | — | — | CN | disclosed |
| US-8309739-B2 | Chemical compounds | SYNGENTA LIMITED (GB) | 2012-11-13 | — | — | US | disclosed |
| US-8309739-B2 | Chemical compounds | SYNGENTA LIMITED (GB) | 2012-11-13 | — | — | US | disclosed |
| US-8309739-B2 | Chemical compounds | SYNGENTA LIMITED (GB) | 2012-11-13 | — | — | US | disclosed |
| CN-101263132-B | Chemical compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-21 | — | — | CN | disclosed |
| US-20110218341-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-09-08 | — | — | US | disclosed |
| US-20110218341-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-09-08 | — | — | US | disclosed |
| US-20110218341-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-09-08 | — | — | US | disclosed |
| US-20110178143-A1 | THERAPEUTIC COMPOUNDS | ALLERGAN, INC. (US) | 2011-07-21 | — | — | US | disclosed |
| US-7960310-B2 | Method of combating and controlling insects | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-14 | — | — | US | disclosed |
| EP-1919886-B1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-10-06 | — | — | EP | disclosed |
| EP-2188261-A1 | THERAPEUTIC COMPOUNDS | Allergan, Inc. (US) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009023757-A1 | THERAPEUTIC COMPOUNDS | ALLERGAN, INC. (US) | 2009-02-19 | — | — | WO | disclosed |
| US-20080300285-A1 | Chemical Compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2008-12-04 | — | — | US | disclosed |
| US-20080300285-A1 | Chemical Compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2008-12-04 | — | — | US | disclosed |
| US-20080300285-A1 | Chemical Compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2008-12-04 | — | — | US | disclosed |
| CN-101263132-A | Chemical compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2008-09-10 | — | — | CN | disclosed |
| EP-1919886-A2 | CHEMICAL COMPOUNDS | Syngeta Participations AG (CH) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007020377-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2007-02-22 | — | — | WO | disclosed |
| WO-2007020377-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178143-A1 | THERAPEUTIC COMPOUNDS | GOT2, GOT1, ANXA5 | RAB9A 2294/4885LMNA 2315/4885CYP3A4 675/4885 |
| US-20080300285-A1 | Chemical Compounds | CHRM5, OR10J3, CHRM3 | RAB9A 1123/4885LMNA 4704/4885CYP3A4 1480/4885 |
| US-20110218341-A1 | CHEMICAL COMPOUNDS | OR10J3, NR0B1, NR0B2 | RAB9A 1311/4885LMNA 4629/4885CYP3A4 1653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.