SCHEMBL20072040

SCHEMBL20072040

Cc1ncc(N2c3ccc(-c4ccccc4)cc3N(c3cnc(C)c(C)n3)C2C2N(c3cnc(C)c(C)n3)c3ccc(-c4ccccc4)cc3N2c2cnc(C)c(C)n2)nc1C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 1/20 0.34
CHRNA7 P36544 2/20 0.33
KCNH2 Q12809 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
GAA P10253 1/20 0.33
KDM4E B2RXH2 3/20 0.32
MAPT P10636 3/20 0.32
TP53 P04637 2/20 0.32
HPGD P15428 2/20 0.32
TSHR P16473 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
HSD17B10 Q99714 2/20 0.32
ALDH1A1 P00352 1/20 0.32
PKM P14618 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32
PDE10A Q9Y233 4/20 0.32
LMNA P02545 1/20 0.32
ATP1A1 P05023 1/20 0.32
ATP1B1 P05026 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20062936 0.80 FLT3 (0.35) FLT3CHRNA7KCNH2L3MBTL1GAA
SCHEMBL20681868 0.74 TSHR (0.37) L3MBTL1GAAKDM4EMAPTTP53
SCHEMBL20681878 0.72 NR1H2 (0.34) TP53HPGDTSHRHSD17B10LMNA
SCHEMBL18911784 0.71 HTR1A (0.40) GAAKDM4EMAPTTP53HPGD
SCHEMBL20072057 0.70 TNKS2 (0.31)
SCHEMBL20072047 0.67 ESR1 (0.40) KDM4EMAPTTP53SMN1; SMN2HSD17B10
SCHEMBL18911785 0.63 FAAH (0.36) MAPTTSHRALDH1A1
SCHEMBL20681918 0.63 HCRTR1 (0.43) KCNH2L3MBTL1KDM4EMAPTTP53
SCHEMBL18911788 0.61 HTR7 (0.44) L3MBTL1MAPTTP53TSHRSMN1; SMN2
SCHEMBL5068071 0.61 ALDH1A1 (0.43) FLT3L3MBTL1GAAKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed