SCHEMBL20062936

SCHEMBL20062936

Cc1ncc(N2/C(=C3/N(c4cnc(C)c(C)n4)c4ccc(-c5ccccc5)cc4N3c3cnc(C)c(C)n3)N(c3cnc(C)c(C)n3)c3cc(-c4ccccc4)ccc32)nc1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT3 P36888 2/20 0.35
GAA P10253 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PDE10A Q9Y233 2/20 0.32
COMT P21964 1/20 0.32
FGFR1 P11362 1/20 0.32
DYRK3 O43781 1/20 0.32
CLK1 P49759 1/20 0.32
CLK2 P49760 1/20 0.32
CLK3 P49761 1/20 0.32
GSK3B P49841 1/20 0.32
CDK5 Q00535 1/20 0.32
DYRK1A Q13627 1/20 0.32
CDK5R1 Q15078 1/20 0.32
DYRK2 Q92630 1/20 0.32
CLK4 Q9HAZ1 1/20 0.32
DYRK1B Q9Y463 1/20 0.32
TYMS P04818 1/20 0.32
CYP11B1 P15538 2/20 0.31
CYP11B2 P19099 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20072040 0.80 FLT3 (0.34) FLT3GAAL3MBTL1PDE10ACOMT
SCHEMBL20062892 0.77 RECQL (0.43) GAAL3MBTL1TYMS
SCHEMBL20062913 0.74 GAA (0.36) GAAL3MBTL1KDM4EMAPTMAPK1
SCHEMBL20062885 0.71 HPGD (0.34) GAAL3MBTL1COMTTYMSKDM4E
SCHEMBL18905746 0.70 ALDH1A1 (0.43) GAATYMSKDM4EMAPTMAPK1
SCHEMBL20062920 0.68 RAB9A (0.38) GAAL3MBTL1KDM4EMAPTMAPK1
SCHEMBL19343013 0.66 HSP90AA1 (0.45) CYP11B1CYP11B2MAPT
SCHEMBL18905721 0.64 MGLL (0.40) L3MBTL1KDM4EMAPTNPC1RAB9A
SCHEMBL19001734 0.63 OPRK1 (0.43) FLT3L3MBTL1COMTFGFR1GSK3B
SCHEMBL20618844 0.62 OPRK1 (0.45) FLT3GAAFGFR1GSK3BCDK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same CANON KABUSHIKI KAISHA (JP) 2019-01-29 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10193084-B2 2,2′-bibenzo[D]imidazolidene compound having heteromonocyclic groups at the 1-, 1′-, 3- and 3′- positions, and organic light-emitting element and display device containing the same BRD1, DRD1, NR2E3 FLT3 3587/4885GAA 4583/4885L3MBTL1 498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.