Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 4/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20656264 | 0.80 | MAPT (0.61) | MAPTTHRBALDH1A1HPGDPGR | |
| SCHEMBL21413066 | 0.78 | — | — | |
| SCHEMBL20079374 | 0.70 | ALDH1A1 (0.55) | MAPTTHRBALDH1A1HPGDPGR | |
| SCHEMBL18358716 | 0.69 | PSMB8 (0.51) | MAPTTHRBALDH1A1PGRMEN1 | |
| SCHEMBL20079378 | 0.68 | POLB (0.55) | MAPTPGRALK | |
| SCHEMBL20079375 | 0.68 | ALDH1A1 (0.51) | MAPTTHRBALDH1A1HPGDPGR | |
| SCHEMBL20656265 | 0.64 | ALDH1A1 (0.43) | MAPTTHRBALDH1A1HPGDPGR | |
| SCHEMBL21413065 | 0.64 | ALDH1A1 (0.52) | MAPTTHRBALDH1A1HPGDPGR | |
| SCHEMBL20079414 | 0.64 | PGR (0.35) | PGR | |
| SCHEMBL22064988 | 0.64 | PGR (0.36) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190016701-A1 | TRPA1 MODULATORS | ALGOMEDIX, INC. (US) | 2019-01-17 | — | — | US | disclosed |
| US-9951046-B2 | TRPA1 modulators | ALGOMEDIX, INC. (US) | 2018-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190016701-A1 | TRPA1 MODULATORS | TRPA1, TRPV1, TRPV2 | MAPT 996/4885THRB 1184/4885ALDH1A1 1436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.