Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18358718 | 0.83 | PSMB8 (0.58) | ALDH1A1HPGDL3MBTL1MAPTPSMB8 | |
| SCHEMBL20079383 | 0.82 | POLB (0.51) | ALDH1A1L3MBTL1PGRPOLB | |
| SCHEMBL20656265 | 0.81 | ALDH1A1 (0.43) | ALDH1A1HPGDL3MBTL1MAPTTHRB | |
| SCHEMBL20079416 | 0.74 | ALDH1A1 (0.42) | ALDH1A1HPGDL3MBTL1MAPTTHRB | |
| SCHEMBL21076079 | 0.72 | CA1 (0.39) | ALDH1A1HPGDMAPTPOLBKDM4E | |
| SCHEMBL20656264 | 0.70 | MAPT (0.61) | ALDH1A1HPGDL3MBTL1MAPTTHRB | |
| SCHEMBL13599975 | 0.68 | ALDH1A1 (1.00) | ALDH1A1HPGDL3MBTL1MAPTTHRB | |
| SCHEMBL20079415 | 0.68 | MAPT (0.42) | ALDH1A1HPGDL3MBTL1MAPTTHRB | |
| SCHEMBL20079372 | 0.68 | PGR (0.49) | ALDH1A1HPGDL3MBTL1MAPTTHRB | |
| SCHEMBL20079368 | 0.67 | ALDH1A1 (0.47) | ALDH1A1HPGDL3MBTL1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200179357-A1 | TRPA1 ANTAGONISTS FOR TREATMENT OF DRY EYE, OCULAR PAIN AND INFLAMMATION | ALGOMEDIX INC (US) | 2020-06-11 | — | — | US | disclosed |
| US-9951046-B2 | TRPA1 modulators | ALGOMEDIX, INC. (US) | 2018-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200179357-A1 | TRPA1 ANTAGONISTS FOR TREATMENT OF DRY EYE, OCULAR PAIN AND INFLAMMATION | TRPA1, TRPV1, TRPV2 | ALDH1A1 2926/4885HPGD 1793/4885L3MBTL1 4759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.