SCHEMBL2008083

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2012800	0.87	NPC1 (0.52)	NPSR1MAPTALDH1A1CYP3A4CYP2C19
	SCHEMBL1021267	0.87	MAPT (0.52)	MAPTALDH1A1KMT2ASMN1; SMN2L3MBTL1
	SCHEMBL2009542	0.86	ALDH1A1 (0.50)	MAPTALDH1A1MEN1KMT2ASMN1; SMN2
	SCHEMBL2003352	0.84	ALDH1A1 (0.50)	MAPTALDH1A1MEN1KMT2ASMN1; SMN2
	SCHEMBL2010721	0.84	PKM (0.51)	ALDH1A1MEN1KMT2ASMN1; SMN2L3MBTL1
	SCHEMBL14555299	0.83	HDAC3 (0.50)	MAPTALDH1A1MEN1KMT2ASMN1; SMN2
	SCHEMBL2006326	0.82	ALDH1A1 (0.50)	ALDH1A1SMN1; SMN2L3MBTL1HDAC3HDAC4
	SCHEMBL2005153	0.82	PKM (0.54)	MAPTALDH1A1MEN1KMT2ASMN1; SMN2
	SCHEMBL12569067	0.82	PKM (0.56)	NPSR1MAPTALDH1A1KMT2ASMN1; SMN2
	SCHEMBL2012534	0.81	HSD11B1 (0.59)	ALDH1A1MEN1KMT2ASMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.